Plain-English translation of NCT04013282 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This research study is looking at how your nervous system controls your digestive system, particularly in people living with obesity. Researchers will use a specialized test called ACEM (Adrenergic Cholinergic Enteric Measures/Mapping) to measure how your nerves and stomach work together. The goal is to understand the connection between nerve function, how quickly your stomach empties food, and your weight.
Many people with obesity have problems with digestion and may not feel full properly, but doctors don't fully understand why. This study hopes to discover whether measuring nerve and digestive function could help explain these problems and eventually lead to better treatments.
You likely qualify if…
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If you qualify, you would undergo the specialized ACEM test, which measures how your nerves control your digestive system. Researchers will also review your weight, height, and any digestive symptoms you've experienced. The study compares these measurements to standard tests like gastric emptying studies to see if there are connections between nerve function and digestion in people with obesity.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
United States
Enrollment target
~500 participants
Started
October 2012
Primary completion
October 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
10 Years – 80 Years
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Thomas L Abell
University of Louisville
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.