Plain-English translation of NCT04026360 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study follows children with cystic fibrosis over many years — from infancy through age 18 — to understand what happens in their lungs early on and how that affects their health later. Researchers will track lung function, look for infections and bacteria in the airways, and use imaging to see how the lungs are doing. The goal is to find early warning signs that could help doctors step in with treatment before serious problems develop.
Cystic fibrosis damages the lungs over time, and many patients face serious breathing problems by adulthood. Doctors don't yet fully understand which children will get sicker faster, or what happens in those first few years of life that sets this in motion. By studying infants and children early on, researchers hope to spot the warning signs — like viral infections and changes in lung bacteria — that predict worse outcomes, so treatment can start sooner.
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You and your child would visit the hospital or clinic regularly — at key points from infancy through age 18. At each visit, doctors will check your child's lung function using breathing tests, take images of the lungs using MRI, collect samples (like mucus or saliva) to look for bacteria and viruses, and ask questions about symptoms and quality of life. The study is long-term, but the goal is simple: to understand your child's lung health over time so doctors can spot problems early and help them stay healthier.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Switzerland
Sponsor
Insel Gruppe AG, University Hospital Bern
Collaborators
University Children's Hospital, Zurich, Centre Hospitalier Universitaire Vaudois
Enrollment target
~500 participants
Started
July 2011
Primary completion
August 2050
Age range
0 Years – 18 Years
Last updated on clinicaltrials.gov in November 2020.
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Central contact
Philipp Latzin, MD PhD
University Children's Hospital Bern
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.