Plain-English translation of NCT04036357 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The Plinio Study is a research project that tracks people with non-alcoholic fatty liver disease (a condition where fat builds up in the liver) to understand how the disease progresses and how it affects heart health. Researchers will collect information from about 2,000 participants to identify which patients are at highest risk for developing severe liver scarring and other serious complications.
Fatty liver disease is very common, especially in people with obesity or diabetes, but doctors don't yet fully understand which patients will develop dangerous liver scarring or have the worst outcomes. This study aims to find new ways to predict who is at highest risk so doctors can intervene earlier.
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As a participant, you would share your medical history and current health information with the research team. The study does not involve taking new medications or undergoing experimental treatments — instead, researchers will monitor your health over time using medical records, blood work, and possibly imaging tests to see how your condition changes. You may be asked to complete visits at the hospital or clinic where your information will be collected.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
Italy
Sponsor
University of Roma La Sapienza
Enrollment target
~2,000 participants
Started
November 2011
Primary completion
December 2036
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in August 2019.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Francesco Baratta, MD, PI.
University of Roma La Sapienza
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.