Plain-English translation of NCT04074135 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is tracking people with von Hippel-Lindau disease (a genetic condition that causes tumors in multiple organs) who have pancreatic tumors or cysts. Researchers will follow you over time with imaging scans, blood tests, and urine samples to understand how these pancreatic growths behave and change—helping doctors make better decisions about who needs surgery and when.
Pancreatic tumors in people with von Hippel-Lindau disease can be unpredictable: some stay small and harmless, while others grow and spread. Doctors don't have clear guidelines about who needs surgery and when. This study will gather long-term information to create better, evidence-based treatment recommendations.
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You'll have scheduled visits where researchers collect blood and urine samples and perform imaging scans (like CT or PET scans) to monitor your pancreatic tumors and cysts. Some participants may also receive a special type of scan called a PET/CT once per year. Throughout the study, doctors will also check for other manifestations of von Hippel-Lindau disease in other parts of your body. The study is long-term, with evaluations happening periodically to track changes and guide any future treatment decisions.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
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