Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders — StellaPhase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.
Trial locations(12 sites)
United States
Phoenix Children's Hospital, Phoenix, Arizona Arkansas Children's Hospital, Little Rock, Arkansas Children's Hospital of Orange County, Orange, California UCSF Benioff Children's Hospital, San Francisco, California Children's National Hospital, Washington D.C., District of Columbia John Hopkins University School of Medicine, Baltimore, Maryland Dana Farber Cancer Institute, Boston Children's, Boston, Massachusetts Memorial Sloan Kettering Cancer Center, New York, New York NACHO Consortium, Memphis, Tennessee Children's Medical Center- UTSW, Dallas, Texas Texas Children's Hospital, Houston, Texas University of Wisconsin-American Family Children's Hospital, Madison, Wisconsin Last updated September 2025