Plain-English translation of NCT04094454 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Anal Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Women with anal cancer need radiation therapy to treat their cancer, but this radiation can sometimes damage healthy vaginal tissue over time. This study is testing whether using a specially designed vaginal dilator during radiation treatment can reduce this damage. Researchers will compare two different dilator sizes to see which approach works best.
Radiation therapy cures many anal cancers, but it can cause scarring and stiffness in the vagina that affects quality of life and sexual health. This trial is trying to find a simple way to protect this tissue during treatment and prevent long-term complications.
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You would receive standard radiation therapy to your pelvis and anal area over several weeks (45–60 Gy total dose). During each radiation session, you would use one of two types of vaginal dilators — either a special extended-size one or a regular tampon-sized one — to help protect the vaginal tissue. Researchers will check you at 12 months after treatment to measure any scarring, assess your symptoms and quality of life, and see how well you tolerated the dilator use.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
Germany