Plain-English translation of NCT04098315 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
PRESTIGIO is an Italian registry that gathers detailed medical and laboratory information from people living with HIV whose virus has developed resistance to multiple classes of HIV drugs. Researchers are collecting this information from about 300 patients across Italy to better understand how to treat people with hard-to-treat HIV. By pooling real-world data from many patients over time, the study aims to improve treatment options for people in this situation.
Some people with HIV develop resistance to standard HIV medications, making their infection much harder to treat. This registry exists to collect and study detailed information about how often this happens in Italy, what patterns emerge, and what treatments work best—so doctors can make better decisions for future patients facing similar challenges.
You likely qualify if…
You likely don't qualify if…
If you join, your infectious disease clinic will share your medical records, lab test results, and treatment history with the registry. The data collection will continue for at least three years. You won't need to take any new medication or undergo special procedures—this is purely about gathering and studying your existing health information to help improve HIV care.
AI-generated summary from trial data · Jul 14, 2026 · Not medical advice
Italy
Collaborators
ViiV Healthcare
Enrollment target
~300 participants
Started
December 2017
Primary completion
March 2020
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
14 Years and older
Last updated on clinicaltrials.gov in May 2025.
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Central contact
Antonella Castagna
san raffaele
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.