Plain-English translation of NCT04099823 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand whether MRI scans can show how cerebrospinal fluid (the fluid that surrounds your brain) moves differently in people with brain diseases like Alzheimer's or hydrocephalus compared to healthy people. This study will help doctors better diagnose and understand what's happening in patients' brains.
Many brain conditions involve problems with how this protective fluid flows around the brain, but doctors don't have a good way to see this movement yet. This study hopes to develop a better imaging method to detect these fluid flow problems, which could lead to earlier diagnosis and better treatment.
You likely qualify if…
You likely don't qualify if…
You will fill out a screening form to make sure you don't have any metal implants that would make an MRI unsafe. If you are a woman of childbearing age, you may need a pregnancy test. Then you'll go to the MRI suite for a brain imaging scan. The entire process is non-invasive and uses only imaging to observe how fluid moves in your brain.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
United States
Enrollment target
~50 participants
Started
October 2019
Primary completion
January 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Suson (Sue) Walsh
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.