Plain-English translation of NCT04099992 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether mindfulness meditation—a practice focused on calm awareness and stress relief—can help people with chronic kidney disease (stages 3 and 4) by calming their overactive nervous system. People with kidney disease have a higher-than-normal risk of heart problems, partly because their nervous system stays in a constant state of stress. Researchers believe that mindfulness meditation might reduce this stress safely, without the side effects that come with blood pressure medications.
Current medications that calm the nervous system often cause uncomfortable side effects like fatigue, dizziness, or rebound high blood pressure. This study exists because doctors need safer, gentler options to protect the hearts of people with kidney disease—and mindfulness meditation might be that option.
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You will attend 8 weekly group sessions lasting 2.5 hours each, plus one full day retreat. Depending on which group you are assigned to, you will either learn and practice mindfulness meditation techniques, participate in a general health education program, or combine mindfulness with a nerve stimulation device. The study will measure your blood pressure, heart rate, and stress markers before, during, and after the program to see if the treatment helps.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Sponsor
Emory University
Collaborators
National Center for Complementary and Integrative Health (NCCIH)
Enrollment target
~150 participants
Started
September 2019
Primary completion
September 2026
Age range
40 Years – 80 Years
Last updated on clinicaltrials.gov in October 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jeanie Park, MD
Emory University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.