Plain-English translation of NCT04106830 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is an observational study that uses advanced MRI imaging techniques to understand how certain nerve inflammation diseases affect the brain, spinal cord, and optic nerve. Researchers will take detailed pictures of your nervous system and compare them with blood markers of inflammation to better understand what happens during these diseases. The goal is to identify patterns that could help doctors predict long-term outcomes and develop better treatments.
Current methods of detecting nerve inflammation diseases rely on blood tests and basic MRI scans, but these don't always show all the structural damage happening in the brain and spinal cord. This study uses newer, more advanced imaging techniques to see exactly where and how inflammation damages nerve tissue, which could help doctors better understand why some patients develop severe disability and how to prevent it.
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You would visit the study center to undergo several advanced MRI scans of your brain, spinal cord, and optic nerve. The researchers will also review your medical records and clinical information from when your condition was first diagnosed. You may also have blood work to measure inflammation markers. The study is observational, meaning you are not taking any new medication — the researchers are simply collecting detailed images and information to understand how these diseases progress.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
China
Sponsor
Beijing Tiantan Hospital
Enrollment target
~1,000 participants
Started
January 2019
Primary completion
December 2027
Age range
16 Years – 75 Years
Last updated on clinicaltrials.gov in June 2026.
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Central contact
Yaou Liu, PhD
Beijing Tiantan Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.