Plain-English translation of NCT04107077 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a treatment called laparoscopic hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with advanced stomach cancer that has spread to the lining of the abdomen. During a minimally invasive surgery, doctors will deliver heated chemotherapy directly into the abdominal cavity, where the cancer is located. Researchers want to see if this approach can trigger the body's immune system to fight the cancer more effectively than chemotherapy given through the bloodstream alone.
When stomach cancer spreads to the abdominal lining, it's very difficult to treat with standard chemotherapy alone. This trial is exploring whether delivering heated chemotherapy directly to the affected area during surgery might be more effective and could help the immune system recognize and attack cancer cells better.
You likely qualify if…
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If you qualify, you would undergo a minimally invasive surgical procedure in which doctors place a small camera in your abdomen to visualize the area, then deliver heated chemotherapy directly into the abdominal cavity. Your doctors will monitor your blood work and overall health throughout the study. The trial will track whether the treatment changes how your immune system responds to the cancer and whether it improves your outcomes compared to chemotherapy alone.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
United States