Plain-English translation of NCT04114435 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how the hearts and lungs of babies born very prematurely develop over time. They will use ultrasound imaging (echocardiography) and developmental assessments to see if early heart problems can predict which babies might have breathing or developmental challenges later in childhood.
Babies born extremely early often have different heart and lung pressures than full-term babies, and these differences may affect their long-term health and development. This study aims to find early warning signs that could help doctors identify and support at-risk children sooner.
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You would bring your baby to the hospital or clinic for ultrasound images of the heart at several time points: when your baby is about one week old, around 8 months corrected age, and at term (full 40 weeks). Later visits at 4–9 months, age 3, and age 5 would include ultrasounds and short developmental questionnaires to track your child's growth and progress. The entire study spans five years, but individual visits typically take under an hour.
AI-generated summary from trial data · Aug 9, 2026 · Not medical advice
Canada
Enrollment target
~150 participants
Started
October 2019
Primary completion
November 2023
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
7 Days – 5 Years
Last updated on clinicaltrials.gov in June 2025.
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