Plain-English translation of NCT04136886 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether combining (a chemotherapy drug) with radiation therapy works better than radiation therapy alone for people whose nasopharyngeal cancer has come back after their first treatment. The study wants to see if adding the medication helps control the cancer better and causes fewer serious side effects over time.
When nasopharyngeal cancer returns after initial treatment, radiation alone doesn't always control it well enough, and it can cause serious long-term side effects. Researchers hope that adding chemotherapy will improve how well the treatment works while reducing harmful effects.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to receive either radiation therapy alone or radiation therapy combined with chemotherapy ( given on two days during your radiation course). The radiation treatment delivers its full dose over 27 sessions. You will be monitored during and after treatment to see how well it works and to track any side effects. The study involves regular follow-up visits to assess your response to treatment.
AI-generated summary from trial data · Aug 2, 2026 · Not medical advice
China
Phase
Large-scale testing
Sponsor
Sun Yat-sen University
Collaborators
JiangXi Province Tumor Hospital, Fujian Province Tumor Hospital
Enrollment target
~346 participants
Started
January 2020
Primary completion
December 2027
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in October 2019.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Fei Han, doctor
Sun Yat-sen University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.