Plain-English translation of NCT04157361 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are testing whether analyzing your exhaled breath can help detect and monitor lung disease in asthma and cystic fibrosis. The study collects breath samples from people with these conditions, comparing them before and after treatment, as well as from healthy volunteers. The goal is to develop a simple, non-invasive 'breath test' that could one day help doctors diagnose problems and track how well treatments are working.
Current methods for detecting lung inflammation and infections in asthma and cystic fibrosis often require invasive procedures. This study aims to create a simple breath test that could catch problems earlier and help doctors monitor disease activity without burden on patients.
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If you join this study, you'll provide breath samples by breathing into a special collection device — a simple, painless procedure. Participants with asthma will give samples before starting or changing medications, and again while taking the new treatment. Those with cystic fibrosis will provide samples at different points during their care, including before and after antibiotic treatment. The study also compares results from healthy volunteers to help researchers understand what normal looks like.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Czechia
Collaborators
University Hospital Olomouc
Enrollment target
~450 participants
Started
May 2015
Primary completion
December 2026
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Petr Dzubak, MD, PhD.
The Institute of Molecular and Translational Medicine, Czech Republic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.