Plain-English translation of NCT04163614 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new way to manage fluid removal during hemodialysis treatments for people with kidney failure. Instead of using a one-size-fits-all approach, researchers want to personalize how much fluid is removed from each patient based on their unique blood pressure patterns during dialysis. The goal is to better control blood pressure, remove excess fluid safely, and reduce dangerous drops in blood pressure that can happen during treatment.
Veterans on hemodialysis have very high rates of heart disease and death, often due to having too much fluid in their bodies. Currently, doctors use trial-and-error to figure out how much fluid to remove, which can be risky. This trial exists to develop a more precise, personalized approach that removes the right amount of fluid for each individual patient while keeping them safe.
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If you join this study, you will be randomly assigned to either continue with your usual dialysis care or to the new personalized fluid management approach. If you are in the new approach group, the study team will adjust your target weight each month based on your recent blood pressure patterns during dialysis, rather than your doctor adjusting it by trial and error. Either way, you will continue your regular hemodialysis treatments, and the study team will monitor your blood pressure and fluid status over time.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States