Plain-English translation of NCT04184635 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a device called VA-ECMO — an artificial heart pump that takes over the work of your heart — combined with another supporting device called an IABP, can help people survive a severe, life-threatening heart attack better than standard treatment alone. The trial will enroll 400 patients to see if using this pump early, right when the heart attack happens, gives people a better chance of recovery and survival.
When a heart attack is severe, the heart can suddenly stop pumping effectively, causing the rest of the body's organs to fail. Even with the best current medical care, more than 4 out of 10 people die from this type of crisis. Doctors are using this artificial heart pump more often to keep patients alive, but no one has proven yet whether using it early — right at the start — actually saves more lives.
You likely qualify if…
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If you join this trial, you will be randomly assigned to receive either the artificial heart pump (VA-ECMO) plus standard treatment, or standard treatment alone. If you are assigned to receive the pump, doctors will place it through a catheter in your leg artery, usually within hours of your heart attack, while you are in intensive care. You will stay in the hospital for close monitoring and follow-up visits to track your recovery, organ function, and survival over time.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
France
Sponsor
Assistance Publique - Hôpitaux de Paris
Enrollment target
~400 participants
Started
October 2021
Primary completion
October 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Alain COMBES, MD, PhD
Centre Hospitalier Universitaire Pitié-Salpêtrière Paris
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.