Plain-English translation of NCT04209218 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Lung Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing two things during lung cancer surgery: (1) whether keeping your blood pressure very stable during the operation—within a tight range—reduces complications and improves long-term survival, and (2) whether a single dose of , an anti-inflammatory medication, provides similar benefits. Some patients will receive careful blood pressure management, others routine care; some will receive the medication, others a placebo (an inactive injection). The researchers believe both approaches may help protect your heart, kidneys, and brain during surgery and help you live longer afterward.
During lung cancer surgery, blood pressure often drops unexpectedly, which can damage vital organs and shorten survival. Recent small studies suggest that keeping blood pressure stable during surgery and using a low dose of anti-inflammatory medication may prevent these complications, but large-scale evidence is missing. This trial will provide clear answers about whether these two approaches actually work.
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You will be randomly assigned to one of four groups that combine two approaches: routine or careful blood pressure management during your surgery, plus either the anti-inflammatory medication or a placebo injection before anesthesia begins. Your medical team will monitor your blood pressure closely throughout the operation (as they normally would), and you'll receive standard post-operative care. The study will then track your recovery and long-term health outcomes for at least a year after surgery, checking for complications and survival.
AI-generated summary from trial data · Aug 1, 2026 · Not medical advice
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