Plain-English translation of NCT04226313 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Cervical cancer is preventable, but many women skip screening appointments. This trial is testing whether giving women a self-sampling device to use at home—instead of requiring a clinic visit—makes screening easier and helps more women get tested. Researchers will compare three ways of delivering the device: by mail to a general list of women, by mail through a gynecologist, or by pickup at a general practitioner's office.
In the Czech Republic, about 800 women are diagnosed with cervical cancer and 400 die from it each year, even though screening exists. The main problem is that many women don't attend screening appointments. This trial is testing whether home-based screening could encourage more women—especially those who have skipped appointments for years—to participate.
You likely qualify if…
You likely don't qualify if…
Depending on which group you join, you will either receive a self-sampling kit by mail at home, receive one from your gynecologist, or pick one up from your general practitioner. You will use the kit to collect a sample yourself at home, then send it back to the lab for testing. The lab will check for the human papillomavirus (HPV), which is the virus that can lead to cervical cancer. Your results will help doctors understand how many women have HPV and whether home-based screening encourages more women to participate.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
Czechia
Sponsor
The Institute of Molecular and Translational Medicine, Czech Republic
Collaborators
National Institute for Cancer Research, Czech Republic
Enrollment target
~15,000 participants
Started
September 2019
Primary completion
December 2026
Age range
30 Years – 65 Years
Sex
Female only
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Marian Hajduch, MD, PhD.
IMTM, Palacky University in Olomouc, Faculty of Medicine and Dentistry
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.