Plain-English translation of NCT04238143 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This trial is testing a new regenerative therapy called adipose-derived biocellular regenerative therapy โ a treatment that uses cells harvested from your own fat tissue to potentially repair damaged joints and reduce arthritis pain. Researchers will test three different versions of this treatment: one using fat-derived cells plus platelet-rich plasma, one combining both of those with additional cell concentrates, and one using cell concentrates alone delivered through an IV. Your results will be tracked for at least two years to see if the treatment safely reduces your pain and improves how your joints work.
Osteoarthritis affects millions of people worldwide and causes chronic pain and disability, but current treatments often only manage symptoms without addressing the underlying joint damage. This trial exists to see whether using your own body's fat cells โ which have natural healing properties โ can actually repair damaged joints and offer longer-lasting relief than existing options.
You likely qualify ifโฆ
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You will have cells harvested from your own fat tissue, which doctors will process and prepare into a therapeutic treatment. Depending on which study group you are assigned to, you will receive either an injection directly into the affected joint, an IV infusion, or a combination of both. After treatment, you will return for regular follow-up visits and imaging tests over a minimum of two years so researchers can track whether your pain improves, your joint function gets better, and the treatment is safe.
AI-generated summary from trial data ยท Jun 5, 2026 ยท Not medical advice
United States