High-dose vitamins and supplements to slow muscle disease progression

This trial is testing whether a combination of over-the-counter vitamins and supplements — including vitamin E, NAC cysteine, L-cystine, nicotinamide, and taurusodiol — can slow down the progression of ALS. The study will enroll 60 people with ALS and track whether this medication helps preserve muscle strength and function over about 13 months. Right now, there are very few effective treatments for ALS, so researchers are testing whether this combination approach might help.

ALS is a rapidly progressive disease with few effective treatments available. Current approved medications only extend survival by a few weeks or help a small number of patients. This trial exists because researchers believe that using multiple vitamins and supplements together — rather than just one medication — might be a safe, affordable way to slow the disease's progression.