Plain-English translation of NCT04255264 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are investigating whether adding resolution molecules—special compounds that help calm inflammation—can reduce both inflammation and insulin resistance in fat tissue taken from people with obesity. This study will look at tissue samples collected during planned abdominoplasty (skin removal) surgery and test whether the results match each person's individual inflammation patterns.
Many people with obesity develop type 2 diabetes because fat tissue becomes inflamed, which interferes with how the body uses insulin. This research aims to understand whether this medication or treatment approach could help reduce that inflammation and potentially prevent or delay diabetes development.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would undergo your scheduled abdominoplasty surgery as planned. During that surgery, researchers will collect a small sample of your fat tissue and test whether adding resolution molecules can reduce inflammation in that tissue. Your involvement is primarily the tissue donation during surgery; the research testing happens in the laboratory afterward.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
Sweden
~18 participants
Started
August 2019
Primary completion
June 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 60 Years
Last updated on clinicaltrials.gov in May 2025.
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Central contact
Emma Borgeson, PhD
Göteborg University
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