Plain-English translation of NCT04258449 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are developing a test called DOvEEgene that can detect cancer of the uterus, fallopian tubes, and ovaries by looking for cancer DNA in cells collected from inside the uterus. This study is testing a new sampling tool called the DOvEEgene Fleur, which is designed to be gentler and cause less discomfort than the current tool used for collecting these cells.
The current sampling tool causes mild to moderate discomfort (about 3.5 out of 10 on a pain scale) because it was designed to remove tissue samples rather than just collect loose cells. This new tool aims to collect cancer cells with less disturbance to the uterus, making the procedure more comfortable while still collecting the cells needed for early cancer detection.
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If you qualify, you will have the new sampling tool used to collect cells from inside your uterus at the time of your scheduled cancer surgery. The procedure takes only a few minutes and is done right before or during your surgical procedure. The cells collected will be tested to look for cancer DNA, and the results may help your doctors better understand your condition.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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