Plain-English translation of NCT04274283 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The Tessa Jowell BRAIN MATRIX is a large study designed to help doctors better understand brain tumors by studying the DNA and molecular changes inside each tumor. Researchers will collect tumor samples and blood samples from patients with newly diagnosed or recurring brain tumors, then analyze these samples to create a precise genetic 'fingerprint' of each tumor. This information will help guide which treatments work best for each individual patient.
Brain tumors are very difficult to treat because of where they're located in the brain and how quickly they grow into surrounding brain tissue. By understanding the genetic changes that make each tumor unique, doctors hope to develop targeted treatments that are more effective and cause fewer side effects, ultimately improving survival and quality of life for patients.
You likely qualify if…
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If you qualify, you will undergo surgery to remove or sample your tumor — this is standard care that would happen whether or not you were in the study. During surgery, researchers will collect a small sample of your tumor tissue and a sample of your blood. These samples will be analyzed to map out the genetic changes in your specific tumor, and the information will be added to a research database to help develop better treatments for future patients.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
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