Plain-English translation of NCT04280510 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Celiac Disease research guide →This study is trying to understand why the immune system attacks the intestines in conditions like celiac disease, refractory celiac disease, and inflammatory bowel disease. Researchers will collect blood and tissue samples from patients with these conditions—as well as from people without intestinal disease—to study how the immune system malfunctions. By comparing these samples, scientists hope to learn what causes these diseases and why some patients develop serious complications.
Currently, doctors don't fully understand why immune-related intestinal diseases develop or why some patients become resistant to standard treatments. This research aims to fill that knowledge gap so that better treatments can be developed in the future.
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If you enroll, you will donate blood and possibly tissue samples from your intestines (if you're having a biopsy for clinical reasons). The researchers will analyze these samples to understand how your immune system is responding. You may be asked to visit the study center one or more times, and the study team will explain exactly what to expect during your first visit. The study does not involve taking medication—it is purely observational.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
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