Plain-English translation of NCT04304898 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The I-FILE study is testing whether patients can safely monitor their own lung disease at home using a simple breathing device called a spirometer. Researchers want to see if this approach helps detect when the disease is getting worse, so doctors can step in earlier with treatment. The study also aims to improve questionnaires that measure how the disease affects daily quality of life.
Currently, patients with scarring lung disease must visit hospitals regularly for breathing tests and check-ups, which is time-consuming and burdensome. This study explores whether home monitoring using eHealth technology could catch disease changes faster and with less disruption to patients' lives.
You likely qualify if…
You likely don't qualify if…
You would use a home spirometry device to measure your lung function daily for the first three months, then once per week for the remaining time. Every six months, you would complete brief online questionnaires about how the disease affects your daily life. All your results are encrypted and sent automatically to a secure server. The entire study lasts up to 2 years, and you can participate from home with minimal travel to the hospital.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Netherlands
Sponsor
Erasmus Medical Center
Enrollment target
~700 participants
Started
May 2020
Primary completion
July 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Marlies Wijsenbeek, MD PhD
Erasmus Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.