Plain-English translation of NCT04322383 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called for people with a rare type of blood cancer called hairy cell leukemia that has come back or stopped responding to standard chemotherapy. works by targeting specific proteins that help cancer cells grow, and early compassionate use has shown promising results in some patients with this type of leukemia. This study wants to see how well the medication works and how safe it is in a larger group of people.
People with this particular form of hairy cell leukemia currently have very limited treatment options and poor survival outcomes when standard chemotherapy stops working. This medication has already helped some patients on a case-by-case basis, but doctors need to study it properly in a clinical trial to confirm it actually works and understand how to use it safely.
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As a participant, you would take as an oral pill at home according to a set schedule. You would come to the National Cancer Institute for regular clinic visits (likely every few weeks) where doctors will check your blood counts, monitor your disease with tests like bone marrow exams, and watch for any side effects. The trial will track how well the medication is working for you over time, and you will be part of a group of up to 40 people receiving this treatment so doctors can learn whether it is effective and safe.
AI-generated summary from trial data · Jul 22, 2026 · Not medical advice
United States