Plain-English translation of NCT04330846 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different approaches to treating intestinal narrowing (called stenosis) that occurs in Crohn's disease patients. Some participants will receive endoscopic treatment—which uses a balloon or metal stent inserted through a scope to widen the narrowed area—while others will have surgery to remove the affected section of intestine. The study wants to compare how well each approach works, how it affects quality of life, and the costs involved.
Doctors currently recommend surgery as the standard first treatment for this type of intestinal narrowing in Crohn's disease, but there are no head-to-head studies comparing it to minimally invasive endoscopic methods. Early research suggests the endoscopic treatment may be just as effective, cheaper, and cause fewer long-term problems, so this trial aims to get solid evidence comparing both approaches.
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If you join this study, you will be randomly assigned to receive either endoscopic treatment (balloon dilation or metal stent placement) or surgery. You will be admitted to a short-stay unit after your procedure and may need up to two endoscopic treatments spaced 2–4 weeks apart if assigned to that group. If you receive a metal stent, it will be removed after 4 weeks. The study will follow your recovery, quality of life, and outcomes over time to see which approach works better for you.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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