Plain-English translation of NCT04340024 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are looking for biological clues in your blood and tissue that can predict how well your body will tolerate radiation therapy for cancer. By studying samples from patients who have had success with radiation and those who experienced severe side effects, scientists hope to develop tests that can help doctors personalize treatment plans and reduce harmful effects before they happen.
Some cancer patients respond very well to radiation therapy, while others experience serious side effects—but doctors cannot reliably predict who will have problems beforehand. This study aims to discover genetic and biochemical markers that could help predict radiation sensitivity, allowing doctors to adjust treatment plans to keep patients safer.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will donate a blood sample and possibly a small tissue sample (tumor tissue paired with normal tissue). The researchers will process these samples in the laboratory to analyze your genes and biochemical markers. This is a one-time collection; there are no ongoing visits or medications involved. Your samples will be studied to help scientists understand what makes some people more or less sensitive to radiation.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Singapore
National Medical Research Council (NMRC), Singapore, Duke-NUS Graduate Medical School
Enrollment target
~5,000 participants
Started
September 2015
Primary completion
December 2026
Age range
21 Years – 99 Years
Last updated on clinicaltrials.gov in June 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Melvin Chua, MD
National Cancer Centre, Singapore
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.