Plain-English translation of NCT04342429 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is the first research study to carefully examine how well intensity-modulated proton therapy works for treating small cell lung cancer. Proton therapy is a type of radiation treatment that some doctors believe may damage the heart and nearby tissues less than traditional radiation therapy. The study will track patients receiving this treatment and compare their side effects to patients who received older radiation methods.
Small cell lung cancer grows quickly and requires strong radiation therapy, but traditional radiation can sometimes harm the heart and other organs near the lungs. Proton therapy might be gentler on these sensitive areas, and researchers want to measure whether this newer treatment actually does cause fewer heart-related complications.
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You would come to Emory University for proton radiation therapy as your cancer treatment, with imaging scans done throughout your course to monitor how the tumor is responding. Researchers will take detailed measurements of your radiation doses and watch carefully for side effects, particularly heart problems, lung inflammation, and esophageal irritation. The study will compare your outcomes to patients who received traditional radiation therapy in the past.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States
Sponsor
Emory University
Enrollment target
~30 participants
Started
March 2020
Primary completion
May 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kristin Higgins, MD
Emory University-Winship Cancer Institute
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.