Plain-English translation of NCT04352244 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying fat tissue from people having planned abdominal surgery or biopsies to understand how different types of fat cells work and affect overall health. By examining these tissue samples in detail — looking at their genetics, chemistry, and structure — scientists hope to learn more about how fat tissue influences metabolism and disease risk, especially for conditions like type 2 diabetes.
Scientists don't fully understand why some people's fat tissue increases their risk for metabolic diseases like type 2 diabetes and obesity, while others remain healthier. This research aims to map out these differences so doctors can eventually develop personalized treatments tailored to each person's unique fat tissue biology.
You likely qualify if…
You likely don't qualify if…
If you qualify, your involvement would be straightforward: researchers would collect a small sample of fat tissue during your already-planned surgery or biopsy — no extra procedures needed. The tissue samples are then studied in the laboratory using advanced imaging and genetic analysis to understand fat cell biology. Your participation requires attending any scheduled study visits and providing informed consent, but the tissue collection happens during your clinically necessary procedure.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
Beth Israel Deaconess Medical Center
Collaborators
Joslin Diabetes Center, Chan Zuckerberg Initiative
Enrollment target
~40 participants
Started
March 2020
Primary completion
June 2027
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in October 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Mary Elizabeth Patti, MD
Joslin Diabetes Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.