Plain-English translation of NCT04353960 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is studying how the heart responds during eye muscle surgery in children. Researchers will measure heart rate changes when eye muscles are gently pulled during surgery, and they want to see if an anticholinergic medication given before surgery affects this response. The goal is to understand this reflex better and potentially improve safety during these common procedures.
During eye muscle surgery, it's well known that the heart sometimes slows down unexpectedly—a reflex doctors call the oculocardiac reflex. This study aims to understand whether giving certain medications before surgery can help prevent or reduce this response, making surgery safer for children.
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If you join this study, you'll be part of either the group that receives anticholinergic medication before surgery or the group that doesn't receive it. Before, during, and after your scheduled eye muscle surgery, doctors will carefully monitor your heart rate and record it along with information about your age, weight, medications, and breathing patterns. The surgery itself is not changed—researchers are simply collecting additional information to understand how different medications affect the heart's response during the procedure.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Enrollment target
~4,000 participants
Started
September 1992
Primary completion
December 2035
Age range
1 Month – 100 Years
Last updated on clinicaltrials.gov in July 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Robert W Arnold, MD
Alaska Blind Child Discovery
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.