Testing a New Medication to Reduce Hearing Voices in Psychosis

This trial is testing whether a medication called Rivastigmine can help reduce auditory hallucinations—hearing voices that aren't there—in people with psychosis. About one-third of people with psychosis don't respond well to standard antipsychotic medications, so researchers are exploring whether this medication might work differently to help these voices go away. The study also includes healthy volunteers to help understand how the brain processes sound and perception.

Hearing voices is one of the most distressing and dangerous symptoms of psychosis, and current medications don't work for everyone. By understanding how the brain creates these false perceptions, researchers hope to develop new, better treatments based on how the brain actually works.