Plain-English translation of NCT04366999 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is testing whether weight loss surgery can improve a condition called fatty liver disease with fibrosis (scarring). Researchers will follow patients who are already planning to have weight loss surgery and compare three different surgical techniques to see which works best for helping the liver heal.
Fatty liver disease is common in people with obesity, and scarring can develop over time, leading to serious liver problems. This study aims to understand whether weight loss surgery can reverse this damage and which surgical approach is most effective.
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If you join this study, you will undergo one of three types of weight loss surgery (all are standard procedures your surgeon would normally perform). You will then return for regular visits where researchers will monitor your liver health through blood tests, imaging scans, and possibly biopsies to see how well your liver improves after surgery. The study follows you over time to track your progress and compare how the different surgical approaches work.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
China
Sponsor
Beijing Friendship Hospital
Collaborators
Beijing Tiantan Hospital, Beijing Hospital (only for Base-NAFLD)
Enrollment target
~320 participants
Started
April 2020
Primary completion
December 2024
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
16 Years – 65 Years
Last updated on clinicaltrials.gov in May 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Zhongtao Zhang, M.D.;Ph.D.
Beijing Friendship Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.