Plain-English translation of NCT04368806 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing a treatment called , which uses your own stem cells from fat tissue to treat knee osteoarthritis. Researchers will collect fat tissue from your abdomen, process the stem cells in a lab, and inject them directly into your knee. The goal is to see if this treatment can reduce pain and improve how well your knee works compared to a placebo injection.
Knee osteoarthritis causes chronic pain and limits daily activities, and current treatments don't work well for everyone. This trial is exploring whether using your own stem cells might repair knee tissue and provide better long-term relief than standard treatments.
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You would visit the clinic 8 times over 48 weeks (about one year). At your second visit, doctors will collect fat tissue from your abdomen using a needle procedure. Two weeks later, you'll receive an injection of either the stem cell treatment or a placebo into your knee. You'll then have follow-up visits at 4 weeks, 12 weeks, 24 weeks, 36 weeks, and 48 weeks to check your pain levels, function, and any side effects. The entire study lasts one year.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
United States