Plain-English translation of NCT04377490 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying how COVID-19 affects the body's blood clotting system in hospitalized patients. When you have severe COVID-19 pneumonia, your body's inflammation and clotting mechanisms can interact in dangerous ways, potentially leading to blood clots. This study collects blood samples and imaging scans to understand these patterns better.
Patients with severe COVID-19 pneumonia appear to have a higher risk of developing blood clots, which can be life-threatening. By understanding how the virus affects clotting, doctors hope to better prevent and treat this serious complication.
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If you join, you will have blood samples taken weekly while hospitalized to measure clotting factors and blood markers. You will also have ultrasound imaging of your legs to check for blood clots. Additional blood tests will be done on the day you're admitted and four weeks after admission to check for specific antibodies. The study is observational, meaning you receive standard hospital care while researchers monitor your blood clotting patterns.
AI-generated summary from trial data · Jul 8, 2026 · Not medical advice
France
Enrollment target
~100 participants
Started
May 2020
Primary completion
October 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Michel Slama, Pr
CHU Amiens
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.