Plain-English translation of NCT04389463 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how COVID-19 affects recovery after heart and lung surgery. When you have both surgery and an active viral infection at the same time, your body faces extra stress that could make breathing problems and other complications more likely. This study will compare patients who had surgery while COVID-positive to those who had surgery while COVID-negative, to learn what risks exist and how to protect patients better.
Heart and lung surgery already puts stress on your body and breathing. COVID-19 also affects the lungs and causes inflammation. Doctors need to know whether having both at the same time creates serious additional risks, so they can prepare better care plans.
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You would not need to visit a clinic or take any new medications. Instead, researchers would collect information from your medical records about your surgery, your COVID-19 status, and how you recovered in the weeks afterward. The study is following about 350 patients total to understand the differences in how people heal.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
France
Enrollment target
~350 participants
Started
May 2020
Primary completion
May 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Mickael VOURC'H, MD
Nantes University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.