Plain-English translation of NCT04402086 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers at Yale are building a collection of blood, saliva, urine, stool, and tissue samples from people with various rheumatic diseases. By studying these samples side-by-side, scientists hope to understand what causes these diseases and how they differ from each other. This resource will help researchers develop better treatments in the future.
Rheumatic diseases are complex, and researchers don't yet fully understand why some people develop them or how to best treat each type. By comparing biological samples from many patients with different rheumatic diseases, scientists can look for patterns and differences that might lead to new insights and better care.
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If you join, you'll be asked to donate biological samples during visits to Yale Rheumatology clinics. This typically includes a blood draw, and may also include samples of saliva, urine, stool, or a small skin biopsy (a tiny sample of skin taken with a numbing medicine). Your samples will be stored and studied by researchers to help them learn more about rheumatic diseases. There is no medication to take, and your participation helps contribute to a large research resource that many scientists will use over time.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
Yale University
Collaborators
Rheumatology Research Foundation
Enrollment target
~5,000 participants
Started
August 2020
Primary completion
June 2030
Age range
18 Years – 99 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Stephanie Perez, MS, BS
Yale University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.