Plain-English translation of NCT04406831 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying tiny molecules called microRNAs found in blood to see if they can help diagnose pancreatic cancer earlier and predict how well treatment will work. This study will compare blood samples from people with newly diagnosed advanced pancreatic cancer to samples from healthy people without cancer. The goal is to develop a simple blood test that could improve how doctors understand and treat pancreatic cancer.
Currently, pancreatic cancer is often caught at an advanced stage, and doctors don't have reliable ways to predict which patients will benefit most from their treatment. This research aims to fill that gap by finding blood-based markers that could help with earlier diagnosis and better predict treatment success.
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If you join this study, you will have blood drawn at your first visit before starting cancer treatment, and then monthly throughout your treatment. Researchers will analyze these blood samples to look for specific microRNA patterns. The study will track how your cancer responds to treatment over time and compare your results with healthy volunteers who donate a single blood sample as a reference. Your participation helps build knowledge that could eventually lead to better diagnostic and predictive blood tests for pancreatic cancer patients.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
United States
Sponsor
Nuvance Health
Enrollment target
~200 participants
Started
April 2015
Primary completion
April 2030
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2026.
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Central contact
Pramila Krumholtz, RN
Nuvance Health
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.