Plain-English translation of NCT04428515 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a pilot study testing a new imaging technology called photoacoustic imaging to help doctors monitor how well radiation therapy is working for head and neck cancer patients. The imaging technology takes pictures of lymph nodes (small glands that can be affected by cancer) during treatment to see if the cancer is responding. The researchers want to find out if this new imaging tool can help predict which patients will benefit most from their treatment.
Currently, doctors have to wait weeks or months after radiation therapy is finished to use standard imaging like MRI to see if the treatment worked. This new imaging technology could potentially show treatment response much sooner, helping doctors adjust treatment plans faster and predict outcomes earlier.
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You would receive standard radiation therapy for your head and neck cancer as planned. During your 7-week treatment period, you would have 5 imaging scans using the new photoacoustic imaging technology to monitor how your lymph nodes are responding. About 10–12 weeks after your radiation therapy ends, you would have a standard MRI scan as part of your regular care. A researcher will measure your lymph nodes to determine if you responded well to treatment. The whole study takes about 3–4 months of your time.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
Canada
Sponsor
Sunnybrook Health Sciences Centre
Enrollment target
~50 participants
Started
April 2019
Primary completion
April 2024
This trial's estimated completion date has passed — the record may not be fully up to date.
Last updated on clinicaltrials.gov in December 2023.
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