Plain-English translation of NCT04430075 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is studying the Edwards PASCAL Transcatheter Valve Repair System, a device designed to repair a leaky mitral valve (a valve in your heart) without open-heart surgery. Researchers are collecting data on how safe this treatment is and whether it improves heart function and quality of life for patients who have already decided to receive it.
Mitral valve leakage can make your heart work harder and cause shortness of breath, fatigue, and other problems. This trial exists to ensure that this newer repair device is working safely and effectively in real-world conditions across Europe.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will receive the valve repair procedure using this new device. After the procedure, you will attend follow-up visits where doctors will monitor how well the repair is working, check your heart function, and ask about your symptoms and quality of life. The study is collecting data from about 1,000 patients across Europe to ensure the device is safe and effective.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Austria
Germany