A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

Completed

Plain-English translation of NCT04435366 on ClinicalTrials.gov ↗ · Source last updated October 2025 · How we translate trials

Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.

Trial locations(205 sites)

United States

Retina-Vitreous Associates Medical Group, Beverly Hills, California

Retinal Diagnostic Center, Campbell, California

Eye Medical Center of Fresno, Fresno, California

Retina Consultants of Orange County, Fullerton, California

University of California, San Diego, La Jolla, California