Plain-English translation of NCT04447911 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether empagliflozin (Jardiance), a medication originally designed for diabetes, can help treat chronically low sodium levels in the blood. Low sodium is a common problem in hospitalized patients and can cause serious complications. Researchers want to see if this medication works better than a placebo (inactive pill) to bring sodium levels back to normal.
Current treatments for low blood sodium — like restricting how much fluid you drink — don't work well enough for many patients. This medication may offer a new, more effective option by helping your kidneys remove extra water, which naturally raises sodium concentration in your blood.
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You will take either the study medication or a placebo pill once a day for 30 days. You'll need to visit the clinic for blood tests to check your sodium levels and make sure the treatment is working safely. Researchers will monitor you throughout the month to see if the medication helps raise your sodium levels back to normal.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Germany
Netherlands
Switzerland