Plain-English translation of NCT04455906 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Atopic Dermatitis research guide →This research study is trying to understand why some people with atopic dermatitis (eczema) experience more severe symptoms than others. Researchers believe a specific genetic variation may play a role in disease severity. By collecting blood and skin samples from patients, the study team hopes to discover the biological mechanisms that make eczema worse in some people.
Currently, doctors don't fully understand why eczema affects people differently—some have mild symptoms while others struggle with severe, hard-to-treat disease. This study aims to identify the genetic and immune factors that drive more severe eczema, which could eventually lead to better, more personalized treatments.
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You would come for a single visit at Boston Children's Hospital where researchers will ask you questions about your health history and eczema symptoms. During that visit, they will take a small blood sample, collect a swab from your skin, and perform a small skin biopsy (a tiny sample of skin tissue). The entire visit should take a few hours, and there are no ongoing medications or follow-up appointments required as part of this study.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Sponsor
Boston Children's Hospital
Collaborators
National Institute of Allergy and Infectious Diseases (NIAID)
Enrollment target
~111 participants
Started
November 2020
Primary completion
March 2027
Age range
6 Years – 65 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Rachel Dabek, MD. MPH.
Boston Children's Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.