Plain-English translation of NCT04458688 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study is investigating how well ocrelizumab works in treating relapsing multiple sclerosis in both African American and Caucasian patients. Ocrelizumab is an FDA-approved medication that helps reduce MS relapses and slow disability by targeting certain immune cells in the body. Researchers want to understand whether this medication works equally well for people of different racial backgrounds, and whether the imaging scans show similar improvements in the brain and eyes.
Previous research suggests that African Americans with MS may experience a more aggressive form of the disease with more brain lesions and eye damage compared to Caucasians. This study exists to find out whether this medication helps both groups equally, and to better understand any differences in how their disease and treatment response might differ.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
If you join this study, you will visit the research clinic 5 times over two years (roughly every 6 months). At each visit, you'll have advanced MRI brain scans and special eye imaging tests to see how your disease and your brain and eye health are changing. You will continue taking your medication as prescribed by your neurologist โ the researchers are simply following along and measuring how well it's working using these detailed imaging tools.
AI-generated summary from trial data ยท Jul 1, 2026 ยท Not medical advice
United States
Sponsor
Wayne State University
Enrollment target
~80 participants
Started
November 2021
Primary completion
July 2025
This trial's estimated completion date has passed โ the record may not be fully up to date.
Age range
18 Years โ 60 Years
Last updated on clinicaltrials.gov in June 2022.
Reach out to the team running this trial. Response times vary โ some teams are faster than others.
Central contact
Zahid Latif
Wayne State University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first โ no email needed to get started.