Plain-English translation of NCT04459806 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing a new device called the Integra CereLink ICP monitor that measures pressure inside the brain. Doctors use this measurement to care for patients who have suffered traumatic brain injuries or brain bleeding. The study will help doctors understand how well this new device works and how best to use the information it provides.
Brain pressure monitoring is an important tool in caring for critically ill patients with brain injuries, but doctors don't always agree on the best way to use the information or what pressure levels should trigger treatment. This trial aims to better understand how this new monitoring device can improve care for these patients.
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If you are already receiving brain pressure monitoring as part of your medical care, you would continue with the new Integra CereLink ICP monitor device instead of (or in addition to) standard monitoring. Trained nurses will record the pressure readings regularly, similar to current practice. The study will track this data to evaluate how well the device works over time.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
Italy
Collaborators
Integra LifeSciences Corporation
Enrollment target
~250 participants
Started
November 2023
Primary completion
November 2026
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in September 2025.
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Central contact
Giuseppe Citerio, Professor
University of Milano Bicocca
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.