Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).

Completed

Plain-English translation of NCT04472429 on ClinicalTrials.gov ↗ · Source last updated November 2025 · How we translate trials

Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.

Trial locations(84 sites)

United States

The University of Arizona Cancer Center, Tucson, Arizona

City of Hope National Medical Center, Duarte, California

UC Davis Comprehensive Cancer Center, Sacramento, California

Sansum Clinic, Santa Barbara, California

Rocky Mountain Cancer Center, Denver, Colorado