Plain-English translation of NCT04478006 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking for ways to treat childhood leukemia more effectively by understanding each child's unique cancer. Researchers will analyze genetic information from your child's blood and bone marrow samples to see which existing treatments might work best for their specific type of leukemia. The study also aims to develop new antibody-based treatments that could help children whose leukemia doesn't respond to standard therapy.
Currently, doctors use the same treatment approach for most children with leukemia, even though their cancers can be very different at the genetic level. This research exists to create personalized treatment plans — matching each child with therapies that are most likely to work for their individual cancer — and to develop new options for children whose leukemia is hard to treat.
You likely qualify if…
You likely don't qualify if…
If your child is eligible, doctors will collect samples of blood and bone marrow, usually during routine medical visits. These samples will be analyzed in the laboratory to map your child's cancer genetics and test how it responds to different medicines in a controlled setting. This is a research study only — the samples are used to gather information that may help guide treatment decisions, and researchers may also use them to test new antibody-based treatments in laboratory models.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
China
Sponsor
Chinese University of Hong Kong
Enrollment target
~300 participants
Started
July 2020
Primary completion
June 2028
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kathy Chan, Ph. D.
Chinese University of Hong Kong
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.