Plain-English translation of NCT04486495 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →MINIMAX is a research study that tracks women with breast cancer that has spread to the lymph nodes. After you receive chemotherapy (and possibly immunotherapy), doctors will use different methods to check if the cancer in your lymph nodes has responded to treatment. The study compares gentler, less invasive approaches to checking and treating the lymph nodes with more intensive surgical approaches, to understand which are safest and least harmful to quality of life.
Right now, doctors are uncertain about the best way to handle lymph nodes after chemotherapy—whether gentler approaches work just as well as traditional surgery, and how different choices affect patients' daily lives and long-term outcomes. This study will help create clear, evidence-based guidelines so doctors and patients can make the best decision together.
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You will be followed for five years from your diagnosis. You'll complete surveys about your quality of life at the time of diagnosis, one year later, and five years later. Your medical records—including details about your cancer, treatments, and outcomes—will be entered into a research database by trained staff. Researchers will track whether your cancer comes back and how well you're doing over time. There are no additional medications or procedures required beyond your standard cancer treatment.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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