Plain-English translation of NCT04494945 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is testing new ways to find people who carry inherited genes—like BRCA1, BRCA2, or Lynch syndrome genes—that increase cancer risk. Researchers want to see if screening people through saliva samples is effective and sustainable, and whether it helps families get the right cancer prevention care. The study will compare different screening approaches to find the best way to identify at-risk people and support them.
Many people carry genes that significantly increase their cancer risk, but they don't know it. This trial exists to find better, more practical ways to identify these people early and ensure they and their family members receive appropriate screening and prevention care.
You likely qualify if…
You likely don't qualify if…
If you join this study, you would provide a saliva sample for genetic testing and complete a survey about cancer prevention and screening. If your genetic test shows you carry an inherited cancer risk gene, you'll receive genetic counseling to help you understand your results and next steps. The study will track how well this screening approach works and whether it helps families access appropriate care.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
United States