Plain-English translation of NCT04507412 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether a single injection of — a common steroid medication — given during shoulder replacement surgery can reduce pain and help you recover faster. Researchers want to see if this medication helps patients sleep better, need fewer pain pills, and get back to normal activities sooner than those who receive standard surgery care without the steroid injection.
Shoulder replacement surgery is helpful for arthritis, but patients often experience significant pain afterward and may need strong pain medications. This trial exists to find out whether the medication can reduce that post-surgery pain and inflammation, allowing patients to recover more comfortably and return to their daily lives more quickly.
You likely qualify if…
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If you join this trial, you will undergo shoulder replacement surgery as planned, but half of participants will receive a steroid injection during the procedure while the other half receive standard anesthesia without the steroid. You will be monitored during your hospital stay and have follow-up visits where doctors will measure your pain level, shoulder movement, pain medication use, and overall recovery. The study tracks your progress over both short-term (immediate recovery) and long-term follow-ups to compare how well the steroid injection works compared to standard care.
AI-generated summary from trial data · Jun 21, 2026 · Not medical advice
Switzerland
Phase
Post-approval monitoring
Sponsor
Christian Candrian
Enrollment target
~74 participants
Started
September 2020
Primary completion
July 2032
Age range
58 Years – 85 Years
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Christian Candrian, Prof.Dr.med
EOC
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.